31th Nikolas Symposium 2023

Eradicating the neoplastic clone

30th Nikolas Symposium 2022

Neurodegeneration in LCH

29th Nikolas Symposium 2019

Immune Strategies in the Histiocytoses

28th Nikolas Symposium 2018

Myeloid Cell Programming and Differentiation

27th Nikolas Symposium 2017

LCH: The Cell of Origin and a Pathway to a Rationale Cure

26th Nikolas Symposium 2016

Mechanisms of Resistance and Therapeutic Development

25th Nikolas Symposium 2015

Mechanisms and Long term Consequences of Neuroinflammatory Disease

24th Nikolas Symposium 2014

Harnessing Immunology and Inflammation in Neoplasms: Relevance to LCH and Histiocytic Disorders

• 23rd Nikolas Symposium 2013

Cellular Origins  of Dendritic  CelΙs: Implications  for LCH

• 22nd Nikolas Symposium 2012

Cell Signaling and Responses: Pathways to Cure?

• 21st Nikolas Symposium 2011

Genomics and Metabolomics in Dendritic Cells: Are there clues for LCH causes and cures?

• 20th Nikolas Symposium 2010

Mechanisms and therapeutic targets of inflammatory disease of the CNS

• 19th Nikolas Symposium 2009

Viral, autoimmune and neoplastic mechanisms of granuloma formation and possible relevance to LCH

• 18th Nikolas Symposium 2008

The tolerogenic nature of tumor-associated inflammation: relevance for LCH

• 17th Nikolas Symposium 2007

Langerhans Cell Function: Implications for LCH

• 16th Nikolas Symposium 2006

A hematopoietic stem cell disorder?

• 15th Nikolas Symposium 2005

Dendritic cell plasticity

• 14th  Nikolas Symposium 2004

Langerhans cell histiocytosis: Bystander cells, interactions, pathophysiology

• 13th Nikolas Symposium 2003

Langerhans cell histiocytosis: neoplasia or immune dysregulation?

Proceedings by Dr Kim Nichols: Click Here.

• 12th  Nikolas Symposium 2002

Dendritic cell differentiation: Signals, signalling and functional consequences: Clues to possible therapy.

Analysis of the functional consequences of aberrant antigen expression.

• 11th Nikolas Symposium 2001

Acute and chronic cytokine networks leading to tissue damage.

• 10th Nikolas Symposium 1999

Dendritic cells and the brain in LCH.

• 9th Nikolas Symposium 1998

Genetics and animal models of Langerhans Cell Histiocytosis (LCH). Identified the need for animal models

• 8th Nikolas Symposium 1997

Migration and in vivo interactions of immune cells. Led to work on chemokines

• 7th Nikolas Symposium 1996

Apoptosis in LCH. Stimulated work on the cell cycle and survival

• 6th Nikolas Symposium 1995

Cell biology and molecular biology in LCH. Discussed dendritic-cell differentiation and cell survival and death.

• 5th Nikolas Symposium 1993

Langerhans cell histiocytosis therapeutics present and future. Stimulated use of antibodies for localization and treatment of disease

• 4th Nikolas Symposium 1992

The neuropathology and pharmacology of LCH. Led to long-term studies of neurological and psychosocial aspects of the disease

• 3rd Nikolas Symposium 1991

The role of cytokines in LCH. Stimulated much work on cytokines

2nd Nikolas Symposium 1990

Viruses as a possible trigger in LCH – developing a strategy. No evidence for viral aetiology

• 1st  Nikolas Symposium 1989

LCH – an immunological disease? Identified avenues for future research and the importance of determining clonality