• 28th Nikolas Symposium 2018
Myeloid Cell Programming and Differentiation
• 27th Nikolas Symposium 2017
LCH: The Cell of Origin and a Pathway to a Rationale Cure
• 26th Nikolas Symposium 2016
Mechanisms of Resistance and Therapeutic Development
• 25th Nikolas Symposium 2015
Mechanisms and Long term Consequences of Neuroinflammatory Disease
• 24th Nikolas Symposium 2014
Harnessing Immunology and Inflammation in Neoplasms: Relevance to LCH and Histiocytic Disorders
• 23rd Nikolas Symposium 2013
Cellular Origins of Dendritic CelΙs: Implications for LCH
• 22nd Nikolas Symposium 2012
Cell Signaling and Responses: Pathways to Cure?
• 21st Nikolas Symposium 2011
Genomics and Metabolomics in Dendritic Cells: Are there clues for LCH causes and cures?
• 20th Nikolas Symposium 2010
Mechanisms and therapeutic targets of inflammatory disease of the CNS
• 19th Nikolas Symposium 2009
Viral, autoimmune and neoplastic mechanisms of granuloma formation and possible relevance to LCH
• 18th Nikolas Symposium 2008
The tolerogenic nature of tumor-associated inflammation: relevance for LCH
• 17th Nikolas Symposium 2007
Langerhans Cell Function: Implications for LCH
• 16th Nikolas Symposium 2006
A hematopoietic stem cell disorder?
• 15th Nikolas Symposium 2005
Dendritic cell plasticity
• 14th Nikolas Symposium 2004
Langerhans cell histiocytosis: Bystander cells, interactions, pathophysiology
• 13th Nikolas Symposium 2003
Langerhans cell histiocytosis: neoplasia or immune dysregulation?
Proceedings by Dr Kim Nichols: Click Here.
• 12th Nikolas Symposium 2002
Dendritic cell differentiation: Signals, signalling and functional consequences: Clues to possible therapy.
Analysis of the functional consequences of aberrant antigen expression.
• 11th Nikolas Symposium 2001
Acute and chronic cytokine networks leading to tissue damage.
• 10th Nikolas Symposium 1999
Dendritic cells and the brain in LCH.
• 9th Nikolas Symposium 1998
Genetics and animal models of Langerhans Cell Histiocytosis (LCH). Identified the need for animal models
• 8th Nikolas Symposium 1997
Migration and in vivo interactions of immune cells. Led to work on chemokines
• 7th Nikolas Symposium 1996
Apoptosis in LCH. Stimulated work on the cell cycle and survival
• 6th Nikolas Symposium 1995
Cell biology and molecular biology in LCH. Discussed dendritic-cell differentiation and cell survival and death.
• 5th Nikolas Symposium 1993
Langerhans cell histiocytosis therapeutics present and future. Stimulated use of antibodies for localization and treatment of disease
• 4th Nikolas Symposium 1992
The neuropathology and pharmacology of LCH. Led to long-term studies of neurological and psychosocial aspects of the disease
• 3rd Nikolas Symposium 1991
The role of cytokines in LCH. Stimulated much work on cytokines
• 2nd Nikolas Symposium 1990
Viruses as a possible trigger in LCH – developing a strategy. No evidence for viral aetiology
• 1st Nikolas Symposium 1989
LCH – an immunological disease? Identified avenues for future research and the importance of determining clonality